Mathematical Foundation:
The calculator uses stoichiometry to work backwards from CO₂ weight loss:
- Measure weight loss = CO₂ released during decarboxylation
- Calculate moles of CO₂ = weight loss ÷ 44.01 g/mol
- Calculate original THCa = moles CO₂ × 358.47 g/mol (1:1 ratio)
- Calculate percentage = THCa weight ÷ initial sample weight
Best Accuracy with Concentrates:
This method works most accurately with isolates, resin, rosin/BHO, shatter, and hashHigh-purity extracts (>70% cannabinoids) provide the most reliable results.
Flower Analysis - Possible but Complex:
This technique can work for flower if you're certain complete decarboxylation occurred, but requires understanding the limitations:
- Moisture content must be completely eliminated first (pre-dry at 180°F)
- Plant material contains cellulose, lignin, and other compounds that may degrade at decarb temperatures
- Expected range for flower: 15-30% THCa (vs 70-95% for concentrates)
- Larger samples needed (minimum 10-20g) due to lower cannabinoid density
Terpene Volatilization - Critical Limitation:
The biggest source of error comes from terpene evaporation, which falsely increases apparent weight loss:
- Live resin/flower: High terpene content (5-15%) can significantly skew results upward
- Cured extracts: Lower terpene content (1-5%) provides better accuracy
- THCa isolate: Minimal terpenes (<1%) gives highest precision
Temperature Considerations:
Too low (below 200°F): Incomplete decarboxylation, false low results
Too high (above 250°F): THC degradation to CBN, false high results
Optimal: 220-240°F for consistent, accurate results
Bottom Line: This method is most reliable for concentrates and extracts where cannabinoids comprise the majority of the material. For flower or high-terpene extracts, expect some margin of error due to volatile compound loss.